Coach John Kuester said guard Ben Gordon could come off the bench Sunday against the Toronto Raptors after missing eight straight games with a sore left ankle.
Hamilton had been out with a sore right hamstring. The guard appeared in Detroit's season opener on Oct. 28, then didn't take the court again until playing back-to-back games on Dec. 12 and 15. He has missed the past five games.
Prince, a forward, played in the first three games of the season, but has been out since Oct. 31 with a ruptured disk in his lower back.